We study DNA transposons and alternative pre-mRNA splicing in Drosophila and humans. We are also investigating connections between alternative pre-mRNA splicing neurodegenerative disease.
Wang, Q., Conlon, E., Gao, J., Manley, J.L. and Rio, D.C. (2020). Widespread intron retention impairs protein homeostasis in C9ORF72 ALS brains. Genome Research, Genome Res. 2020 Dec;30(12):1705-1715. doi: 10.1101/gr.265298.120. Epub 2020 Oct 14. PMID: 33055097
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