Selected Publications

Ghanim, G., Rio, D.C. and Karam Teixeira, Felipe. (2020). Mechanism and regulation of P element transposition. Open Biology, Open Biol. 2020 Dec;10(12):200244. doi: 10.1098/rsob.200244. Epub 2020 Dec 23. PMID: 33352068

Selected Publications

Wang, Q., Conlon, E., Gao, J., Manley, J.L. and Rio, D.C. (2020). Widespread intron retention impairs protein homeostasis in C9ORF72 ALS brains. Genome Research, Genome Res. 2020 Dec;30(12):1705-1715. doi: 10.1101/gr.265298.120. Epub 2020 Oct 14. PMID: 33055097

Selected Publications

Ghanim, G., Kellogg, E., Nogales, E. and Rio, D.C. (2019). Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts. Nature Struct. Mol. Biol. 26(11):1013-1022. doi: 10.1038/s41594-019-0319-6. PMID: 31659330; PMCID: PMC6948148

Selected Publications

New and views: Rice, P.A. (2019). Structure of the P element transpososome reveals new twists on the DD(E/D) theme. Nat Struct Mol Biol. 2019 Nov;26(11):989-990.

Selected Publications

Wang, Q. and Rio, D.C. (2018). The Junction Usage Model (JUM): A method for comprehensive annotation-free analysis of alternative pre-mRNA splicing patterns. Proc. Natl. Acad. Sci. U.S.A. 115, E8181-E8190. doi: 10.1073/pnas.1806018115 PMID: 30104386; PMCID: PMC6126775

Selected Publications

Lee, Y.J., Wang, Q. and Rio, D.C. (2018). Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5. Genes and Development, 32,1060-1074. doi: 10.1101/gad.316034.118. Epub 2018 Jul 24. PMID: 30042133; PMCID: PMC6075143

Selected Publications

Wang, Q., Abruzzi, K., Rosbash, M. and Rio, D.C. (2018). Alternative splicing diversity and circadian cycling within discreet Drosophila neurons. eLife, Jun 4;7. pii: e35618. doi: 10.7554/eLife.35618. PMID: 29863472; PMCID: PMC6025963

Selected Publications

Teixeira, F.K., Okuniewska, M., Malone, C.D., Coux, R.-X., Rio, D.C. and Lehmann, R. (2017). piRNA-mediated regulation of transposon alternative splicing in soma and germline. Nature 552, 268-272. PMID: 29211718; PMCID: PMC5933846; DOI: 10.1038/nature25018

Selected Publications

Wang, Q., Taliaferro, J.M., Klibaite, U., Hilgers, V., Shaevitz, J. and Rio, D.C. (2016). The PSI-U1 snRNP interaction regulates neural pre-mRNA splicing to control Drosophila courtship. Proc. Natl. Acad. Sci. U.S.A. 113, 5269-5274. PMID:27114556; PMCID: PMC4868454.

Selected Publications

Francis, M.J., Roche, S., Cho, M.J., Beall, E.L., Min, B., Panganiban, R.P., and Rio, D.C. (2016). The Drosophila IRBP bZIP heterodimer binds P element DNA and affects hybrid dysgenesis. Proc. Natl. Acad. Sci. U.S.A., 113, 13003-13008. PMID: 27114556; PMCID: PMC4868454

Selected Publications

Biochemical identification of new proteins involved in splicing repression at the Drosophila P element exonic splicing silencer. Horan, L., Yasuhara, J.C., Kohlstaedt, L.A. and Rio, D.C. (2015). Genes and Development, 29, 2298-2311. PMID:26545814; PMCID: PMC4647562.

Selected Publications

P transposable elements in Drosophila and other organisms. Majumdar, S. and Rio, D.C. (2015). ASM Press. Online in: Microbiol Spectr. 2015 Apr;3(2). pii: MDNA3-0004-2014. Print: Mobile DNA III.

Selected Publications

Mechanisms and regulation of alternative pre-mRNA splicing. Lee, Y. and Rio, D.C. (2015). Ann. Rev. Biochem., 84, 291-323.

Selected Publications

The human THAP9 gene encodes an active P element DNA transposase. Majumdar, S., Singh, A. and Rio, D.C. (2013). Science, 339, 446-448.

Selected Publications