Selected Publications
The human THAP9 gene encodes an active P element DNA transposase. Majumdar, S., Singh, A. and Rio, D.C. (2013). Science, 339, 446-448.
Selected Publications
Mechanisms and regulation of alternative pre-mRNA splicing. Lee, Y. and Rio, D.C. (2015). Ann. Rev. Biochem., 84, 291-323.
Selected Publications
P transposable elements in Drosophila and other organisms. Majumdar, S. and Rio, D.C. (2015). ASM Press. Online in: Microbiol Spectr. 2015 Apr;3(2). pii: MDNA3-0004-2014. Print: Mobile DNA III.
Selected Publications
Biochemical identification of new proteins involved in splicing repression at the Drosophila P element exonic splicing silencer. Horan, L., Yasuhara, J.C., Kohlstaedt, L.A. and Rio, D.C. (2015). Genes and Development, 29, 2298-2311. PMID:26545814; PMCID: PMC4647562.
Selected Publications
Francis, M.J., Roche, S., Cho, M.J., Beall, E.L., Min, B., Panganiban, R.P., and Rio, D.C. (2016). The Drosophila IRBP bZIP heterodimer binds P element DNA and affects hybrid dysgenesis. Proc. Natl. Acad. Sci. U.S.A., 113, 13003-13008. PMID: 27114556; PMCID: PMC4868454
Selected Publications
Wang, Q., Taliaferro, J.M., Klibaite, U., Hilgers, V., Shaevitz, J. and Rio, D.C. (2016). The PSI-U1 snRNP interaction regulates neural pre-mRNA splicing to control Drosophila courtship. Proc. Natl. Acad. Sci. U.S.A. 113, 5269-5274. PMID:27114556; PMCID: PMC4868454.
Selected Publications
Teixeira, F.K., Okuniewska, M., Malone, C.D., Coux, R.-X., Rio, D.C. and Lehmann, R. (2017). piRNA-mediated regulation of transposon alternative splicing in soma and germline. Nature 552, 268-272. PMID: 29211718; PMCID: PMC5933846; DOI: 10.1038/nature25018
Selected Publications
Wang, Q., Abruzzi, K., Rosbash, M. and Rio, D.C. (2018). Alternative splicing diversity and circadian cycling within discreet Drosophila neurons. eLife, Jun 4;7. pii: e35618. doi: 10.7554/eLife.35618. PMID: 29863472; PMCID: PMC6025963
Selected Publications
Lee, Y.J., Wang, Q. and Rio, D.C. (2018). Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5. Genes and Development, 32,1060-1074. doi: 10.1101/gad.316034.118. Epub 2018 Jul 24. PMID: 30042133; PMCID: PMC6075143
Selected Publications
Wang, Q. and Rio, D.C. (2018). The Junction Usage Model (JUM): A method for comprehensive annotation-free analysis of alternative pre-mRNA splicing patterns. Proc. Natl. Acad. Sci. U.S.A. 115, E8181-E8190. doi: 10.1073/pnas.1806018115 PMID: 30104386; PMCID: PMC6126775
Selected Publications
New and views: Rice, P.A. (2019). Structure of the P element transpososome reveals new twists on the DD(E/D) theme. Nat Struct Mol Biol. 2019 Nov;26(11):989-990.
Selected Publications
Ghanim, G., Kellogg, E., Nogales, E. and Rio, D.C. (2019). Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts. Nature Struct. Mol. Biol. 26(11):1013-1022. doi: 10.1038/s41594-019-0319-6. PMID: 31659330; PMCID: PMC6948148
Selected Publications
